MDK and cancer: Importantly, we identified new genes associated with this metastatic cell state including ANXA1, Kallikrein family, FKBP4, Serpin family, CD47, MDK and the sialyl-transferases ST3GAL4 and ST6GALNAC1. These genes have been implicated in cancer development and metastasis among other types of primary malignancies but not in appendiceal mucinous neoplasms.