ANO1 and neoplasm: By immunohistochemistry (IHC), the tumor showed strong, diffuse positivity for DOG1 (ANO1) and CD117, and negativity for SMA, desmin, HMB45, Mel-A, CDK4, MDM2, S100, CKAE1/AE3, CK7, racemase, and PAX8 (Figure 2).