To further reveal the relationship between ITGAV expression levels in clinical samples and the malignant progression of digestive system cancers, we used an online analysis tool to group the four clinical samples of digestive system cancers, STAD, COAD, LIHC, and ESCA, in the TCGA database according to T-stage, N-stage, M-stage, and pathological stage. Here, ITGAV is linked to digestive system cancer.