HLA-C and neoplasm: To comprehensively assess the relationship of ITGAV with immune infiltration and immunomodulation, we analyzed the correlation between the abundance of tumor-infiltrating lymphocytes (TILs) and ITGAV methylation, MHC molecules, immunostimulators, immunoinhibitors, chemokines, and chemokine receptors by Gene Set Variation Analysis(GSVA) (Supplementary Figure S5).