POSTN and neoplasm: We found that tumor cells in the high-risk group had strong cellular communication with myeloid cells through the GAS signaling pathway, with fibroblasts through the GAS and PERIOSTIN signaling pathways, with endothelial cells through the HSPG and PERIOSTIN signaling pathways, and with T/NK cells through the PAR signaling pathway (Supplementary Figures 9A–D).