EPP1 is also associated with disturbances in the iron metabolism: while a pronounced anaemia is only present in a minority of the patients, low serum iron, ferritin and transferrin saturation and hypochromic, microcytic erythrocytes are commonly observed and indicate an iron deficiency (Holme et al., 2007; Delaby et al., 2009; Wahlin et al., 2011b; Balwani et al., 2017; Minder et al., 2021). This evidence concerns the gene FECH and Iron deficiency anemia.