CASP3 and myocardial infarction: Finally, at day 28 post surgery, salidroside administration largely decreased the cross-sectional area of myocardial fibers in myocardial infarction model mice (Fig. 1H–I), which was accompanied by the following changes in apoptosis markers: elevated levels of Bcl-2 and reduced Bax and cleaved caspase 3 levels (Fig. 1J).