In the KEGG enrichment analysis of related genes, we found that the IL-17 signalling pathway and the TNF signalling pathway were the significantly enriched pathways, suggesting that these genes may affect lung carcinogenesis through the immune pathway.IL-17, which is mainly secreted by Th17 cells, is able to promote lung carcinogenesis and progression by inducing tumour angiogenesis and enhancing tumour immune escape [30]. Here, TNF is linked to neoplasm.