MGMT and neoplasm: The generalizability of these findings may also be limited by the favorable early disease course, including a rapid interval between presentation and diagnosis, no tumor growth between the diagnostic and preoperative scans, good Eastern Cooperative Oncology Group Performance Status and limited tumor-associated edema (although there were some key poor prognostic factors, including an unmethylated MGMT promoter and incomplete resection because of the tumor’s proximity to eloquent brain regions).