Mesothelioma cells, orchestrate the release of macrophage-attractant factors such as interleukin (IL)-8, IL-6, C-C motif chemokine ligand 2 (CCL2/MCP-1), G-CSF, GM-CSF, and MIP-1α, key players in sustaining tumor growth19. This evidence concerns the gene CSF2 and mesothelioma.