SCD and leukemia: The smaller volume and perinuclear localization pattern of the mitochondria in P. gingivalis-infected cells were consistent with the mitochondria in leukemia stem cells.49 Interestingly, we also observed mitochondrial swelling and focal cavitation in SCD1-depleted cells, suggesting that SCD1 may also play a role in maintaining the unique mitochondrial morphology of P. gingivalis-infected cells.