METTL16 and colon adenocarcinoma: As shown in Figure 1A, the expression level of METTL16 in the tumor tissues of cholangiocarcinoma (CHOL), head and neck squamous cell carcinoma (HNSC), liver hepatocellular carcinoma (LIHC), Stomach adenocarcinoma (STAD) (P < 0.001), colon adenocarcinoma (COAD), esophageal carcinoma (ESCA) (P < 0.01), is higher than the corresponding control tissues.