CD8A and type 1 diabetes mellitus: Additionally, in accordance with previous observations on the viral role in the manifestation of T1D and observations from the AbATE study on an increase in the detectable viral load in the treated group, Long and colleagues found that Epstein-Barr virus (EBV) reactivation significantly correlated with elevated transcription of EOMES genes in CD8+ T cells (Long et al, 2016).