IL1B and type 1 diabetes mellitus: This aligns with previous research that has shown the inhibitory effects of GABA on several cytokines commonly associated with T1D manifestation and progression, such as IL-2 (Tian et al, 2004), interferon gamma (Tian et al, 2004), IL-6, IL-12 (Reyes-García et al, 2019), IL-1β (Zhao et al, 2014), and TNF-α (Swaroop et al, 2012).