Two-dose regimen of GAD65 Alum, vitamin D, and ibuprofen was assessed on 64 patients with recent-onset T1D aged 10–18 years old (full treatment: 16 patients, placebo + GAD65 Alum + vitamin D: 16 patients, placebo + GAD65 Alum double dose + vitamin D: 16 patients, placebo: 16 patients; Ludvigsson et al, 2020). Here, GAD2 is linked to type 1 diabetes mellitus.