IL1B and type 1 diabetes mellitus: IL-1β—induced inflammatory cell damage in T1D is prominently associated with NLRP3 inflammasome—caspase-1 activity, which detects cellular stress and cell membrane damage and is activated through Toll-like receptor mediated NFκB pathway described in detail elsewhere (Grishman et al, 2012; Niț;ulescu et al, 2023).