In some other studies, ebselen has also been shown to have some effects in decreasing the production of TNFalpha‐induced pro‐inflammatory factors, including IL‐6, IL‐8, monocyte chemoattractant protein‐1 (MCP‐1), and cyclooxygenase (COX2) which can help mediate inflammation in GBM, (Tewari et al. 2009). This evidence concerns the gene TNF and glioblastoma.