Additionally, women with a normal BMI but elevated whole-body fat levels face an increased risk of breast cancer, with an adjusted hazard ratio (HR) of 1.89 (95% CI: 1.21–2.95) for all invasive breast cancer and 2.21 (95% CI: 1.23–3.67) for hormone receptor-positive breast cancer. Here, NR4A1 is linked to breast cancer.