Studies on PPP1R13L suggest that it plays roles in apoptosis, senescence, antioxidation, epithelial-mesenchymal transition (EMT), mitotic spindle regulation, immune responses, and other processes, thereby promoting tumor development and chemoresistance, identifying it as a possible diagnostic marker and treatment target in these cancers [5, 11–15]. This evidence concerns the gene PPP1R13L and neoplasm.