Our previous study found that Meth exposure stimulated the expression of Alzheimer's disease (AD) like pathological proteins, including amyloid‐β42 (Aβ42) and phosphorylated tau (p‐tau) [4, 5], which are commonly expressed in the hippocampus, thereby aggravating neuronal damage and underscoring the importance of selecting hippocampal neurons for this study. This evidence concerns the gene MAPT and Alzheimer disease.