PGAM5 and Cognitive impairment: In concert with our assumption, PARL overexpression markedly ameliorated neuronal loss, mitochondrial injury, and cognitive impairments after Meth exposure; Besides, the Meth‐induced upregulation of PINK1, PGAM5, Parkin, MLKL, RIP1, and RIP3 expression at gene and protein levels was substantially ameliorated, strongly confirming the salutary effects of PARL on Meth‐induced neurotoxicity.