MSA were detected in 70.6% of DM patients in the cohort 1 (anti-Mi2, n=10; -Tif1γ, n=12; -NXP2, n=7; -MDA5, n=5 and -SAE, n=2) AsyS were all positive (anti-Jo1, n=38; -PL7, n=4; -PL12, n=3 and –EJ, n=1), and all IMNM patients were seropositive (anti-SRP, n=13, -HMGCR, n=19). The gene discussed is HMGCR; the disease is dermatomyositis.