Serum IFN-α level was significantly higher in DM (0.07 [0.03-0.23] pg/ml) and ASyS (0.07 [0.02-0.16] pg/ml) compared to HD (0.02 [0.01-0.05] pg/ml; p<0.005 and p<0.05 respectively) whereas it was not significantly different in IMNM (0.03 [0.01-0.09] pg/ml) or IBM (0.02 [0.02-0.03] pg/ml) compared to HD (Figure 1A). The gene discussed is IFNA1; the disease is dermatomyositis.