PIK3CA and intraductal papilloma: Although PIK3CA or AKT mutations are more common in breast intraductal papilloma, AKT1 E17 K mutation was detected in intraductal papilloma of minor salivary glands, and no genetic alterations (BRAF, PI3KCA etc.)were detected in salivary glands intraductal papilloma with previous reports (6, 17, 18).