In addition to administering conventional pharmacological treatments, mainly cholinesterase inhibitors such as carbapenems and doxorubicin that have been shown to be useful in clinical practice (Rolinski et al., 2012; Seppi et al., 2019), clinicians can also inform patients that they can engage in appropriate physical exercise and cognitive training, which may have a beneficial effect on cognitive function in patients with PD (Weintraub et al., 2022). This evidence concerns the gene BCHE and Parkinson disease.