Also, RAR had a slightly higher value (AUC: 0.674, 95%CI: 0.609–0.738) in predicting mortality at 90-d than SOFA score (AUC: 0.669, 95%CI: 0.608–0.731), SIRS score (AUC: 0.544, 95%CI: 0.485–0.602), GCS score (AUC: 0.557, 95%CI: 0.507–0.607), RDW (AUC: 0.671, 95%CI: 0.611–0.731) and Alb (AUC: 0.624, 95%CI: 0.559–0.689). The gene discussed is ALB; the disease is systemic inflammatory response syndrome.