In response to the presence of rhabdoid cells in the tumor, further immunohistochemical studies were conducted to investigate the SWI/SNF chromatin remodeling complex, exhibiting deficiency in SMARCA2 (BRM) while maintaining proficiency in SMARCA4 (BRG1) and SMARCB1(INII) (Figs. 4E–4G). This evidence concerns the gene SMARCA4 and neoplasm.