Similarly, Fawzi et al. (2014) found that in an ALS case with a C9orf72 expansion mutation, TDP-43 retinal pathology was absent; however, they did find p62 and ubiquitin-positive cytoplasmic inclusions, primarily (94.9%) in the inner nuclear layer (INL), likely within amacrine and horizontal cells (Fawzi et al., 2014; Volpe et al., 2015). This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.