CDC42 and lung cancer: Furthermore, Masraksa and colleagues have demonstrated that luteolin can hinder the spread and invasion of lung cancer cells by targeting the signaling pathways of focal adhesion kinase and non-receptor tyrosine kinase (Src/FAK) as well as its downstream pathways involving Ras-related C3 botulinum toxin substrate 1 (Rac1), cell division cycle 42 (Cdc42), and ras homologous gene family member A (RhoA) (Masraksa et al., 2020).