Zhou and colleagues proposed that luteolin alleviates oxidative stress induced by CS in COPD by modulating the transient receptor potential vanilloid type 1 (TRPV1) and cytochrome P450 family 2 subfamily A member 13 (CYP2A13)/nuclear factor erythroid 2-related factor 2 (NRF2) signaling pathways. The gene discussed is TRPV1; the disease is chronic obstructive pulmonary disease.