We then developed a nomogram using TCGA data based on ITGA4 expression, patient age, and cancer type to predict survival probabilities (Figure 3F), which showed strong predictive performance in both training and validation datasets with AUC exceeding 0.7 for 1-, 3-, and 5-year survival (Figures 3G, J), validated by accurate calibration curves (Figures 3H, K). Here, ITGA4 is linked to cancer.