Notably, cancers like GBM, BRCA, ESCA, STES, KIPAN, STAD, HNSC, KIRC, and CHOL consistently showed higher ITGA4 expression in individual and combined databases, while LUAD, KIRP, LUSC, BLCA, READ, and KICH consistently exhibited lower expression. The gene discussed is ITGA4; the disease is glioblastoma.