n = 80 patients Age, median = 69, 70% men and 30% women, 81% had an ECOG performance status at 0–1 at baseline, 19% had elementary as highest education, 30% high school, 26% trade diploma and 21% post‐secondary, 41% had limited cancer health literacy. Types of cancer: NSCLC (55%), malignant melanoma (19%), renal cell carcinoma (9%), and other (17%), treatment: 70% PD‐1/PD‐L1 monotherapy. The gene discussed is RPL17; the disease is hereditary clear cell renal cell carcinoma.