We will discuss this presently, but conversely, many investigations have concluded that necroptosis and/or RIPK3 had a role in cancer mitigation and control (Cho et al., 2024, Colbert et al., 2013, Conev et al., 2019, Ertao et al., 2016, Koo et al., 2015, Morgan and Kim, 2015b, Murphy et al., 2013, Park et al., 2009, Seifert et al., 2016). Here, RIPK3 is linked to cancer.