RIPK3 and neoplasm: There are some data that have suggested that RIPK3 and necroptosis-mediated inflammation contributes to tumorigenesis through an inflammatory and immunosuppressive tumor microenvironment (Jiao et al., 2018, Seifert et al., 2016, Strilic et al., 2016, Vucur et al., 2023, Wang et al., 2018, Zhang et al., 2023, Zhong et al., 2023).