For PALB2 c.1592delT, ATM c.7570G > C, CHEK2 c.1100delC, MCPH1 c.909_921del and RAD50 c.687delT the association with breast cancer was also significant, whereas FANCM c.5101C > T (OR 0.9, 95% CI 0.57–1.28) and c.5791C > T (OR 0.8, 95% CI 0.43–1.61) remained under statistical significance with slightly lower frequency in cases compared to controls (Table 1). Here, MCPH1 is linked to breast carcinoma.