BRCA2 and breast cancer: The overall prevalence of the studied BRCA1/2 variants in the unselected breast cancer cohort was 0.9% (21/2338, of which 7 BRCA1 and 14 BRCA2), which was significantly higher compared to controls (odds ratio [OR] 6.7, 95% confidence interval [CI] 2.24–19.70, p < 0.001).