MCPH1 and breast cancer: MCPH1 c.909_921del and RAD50 c.687delT alleles have both been reported to be enriched in Northern Finnish breast cancer cases [9, 10, 30], here the former showing a twofold enrichment in cases (1.5%, OR 2.1, 95% CI 1.27–3.34, p = 0.004) and the latter over fourfold enrichment (1.2%, OR 4.6, 95% CI 2.34–9.08, p < 0.001).