KEGG analysis revealed enrichment in multiple inflammation-related pathways, including cytokine-cytokine receptor interaction, primary immunodeficiency, tumor necrosis factor (TNF) signaling pathway, IL-17 signaling pathway, and Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway (Fig. 5B). This evidence concerns the gene SOAT1 and inborn error of immunity.