Separately, TET2 deficiency in acute myeloid leukaemia increases the expression of Tetraspanin 13 (TSPAN13) by enhancing m5C modification in its mRNA and stabilising it through YBX1, thereby activating the CXCR4/CXCL12 signalling pathway to promote leukaemia stem cell homing to the BM niche and enhance self‐renewal.138. This evidence concerns the gene TSPAN13 and leukemia.