Research into the pathogenesis of PCOS remains limited (9), but current evidence highlights a notable association between hormonal fluctuations and PCOS pathogenesis, particularly in the levels of insulin, luteinizing hormone (LH), follicle-stimulating hormone (FSH), androgens, estrogens, and progesterone (10) (Figure 1). Here, PLOD1 is linked to polycystic ovary syndrome.