Of these, six potential causal associations showed statistically significant differences in the Mendelian analyses after adjustment for false discovery rate (FDR).Specifically, genetically predicted C-C motif chemokine 28 levels (OR=0.624; 95% CI=0.411-0.948, p = 0.027) were potentially negatively associated with viral encephalitis in the IVW approach. This evidence concerns the gene CCL28 and viral encephalitis.