The immune cells that are then recruited to the site of infection release large quantities of inflammatory mediators such as chemokine (C-C motif) ligand (CCL)7, CCL8, CCL13, CCL17, CD163, CXCL2, CXCL11, IFN-γ, IL-1, IL-2, IL-3, IL-4, IL-6, IL-7, IL-8, IL-9, IL-10, IL-13, IL-15, IL-17, interferon-inducible protein 10 (IP-10), macrophage inflammatory proteins (MIPs), regulated upon activation normal T-cell expressed and secreted (RANTES), soluble tumor necrosis factor receptor-1 (sTNFR1),TNF-α, TNF-β, and TNF-related apoptosis-inducing ligand (TRAIL) (Silva et al., 2023). The gene discussed is TNF; the disease is infection.