NRP1 and COVID-19: Severe COVID-19 infection also causes arterial damage, further increasing NRP-1 expression (Mayi et al., 2021), a contention supported by observations of increased NRP-1 RNA in cells infected with SARS-CoV-2 isolated from bronchoalveolar lavage fluid from patients with COVID-19 (Cantuti-Castelvetri et al., 2020).