An experimental animal infection study undertaken in Rhesus macaques to determine the mechanisms underlying the inflammation and thrombosis seen in SARS-CoV-2 infection, showed activation of IFN-α, IFN-γ, interleukins, and TNF-α in bronchoalveolar samples on the first day of infection (Flaumenhaft et al., 2022). Here, IFNG is linked to infection.