Among these hot words (minimum number of occurrences of a keyword is more than five; 45 words meet the threshold) that co-occur with STING agonist include: STING, cancer immunotherapy, immunotherapy, tumor microenvironment, innate immunity, colorectal cancer, macrophages, type I interferon, diABZI, photothermal therapy, immunogenic cell death, cGAS-STING pathway, combination therapy, SARS-CoV-2, adjuvant, c-di-AMP, cGAS, cyclic dinucleotides, cGAMP, nanoparticles, melanoma, glioblastoma, DMXAA, cancer, antitumor immunity, vaccine, neoantigen, and drug delivery. The gene discussed is CGAS; the disease is colorectal cancer.