Here, we report a long-chain non-coding RNA AC010198.2 as a novel fusion partner of ETV6, showing a karyotype of del(12)(p13p11), with poor prognosis in a post-myeloproliferative neoplasm Myeloproliferative Neoplasms (MPN) AML that has never been reported. Here, ETV6 is linked to acute myeloid leukemia.