SLC5A2 and lung cancer: They found that there was no significant difference in the expression of SGLT2 in primary lung cancer lesions and normal tissues, but the expression of SGLT2 in liver and lymph node metastatic lesions was significantly higher than that in primary lesions, and these results led to the preliminary speculative conclusion that SGLT2 plays a key role in glucose uptake in lung cancer metastasis (21).