TRPV1 and differentiated thyroid carcinoma: (26) found that capsaicin activation of TRPV1 down-regulates the expression of key EMT transcription factors Snail1 and Twist1, and also down-regulates the expression of MMPs-2 and MMPs-9, and ultimately significantly inhibits the migration, invasion and adhesion of bCPAP cells in thyroid papillary carcinoma.