CTNNAL1 and asthma: To confirm the direct link between asthma and the inhibition of the CTNNAL1 gene, a mouse model with a deficiency of the Ctnnal1 protein in bronchopulmonary tissue was created by transduction with AAV5 carrying small interfering RNA (siRNA) sequences targeting the Ctnnal1 gene (37) (Table 1 and Figure 2).