GSTM1 and chronic obstructive pulmonary disease: Case 5. A 78-year-old man with advanced COPD, diabetes, and end-stage ischemic heart disease (LVEF 20%). The patient is in palliative care. Hb 70 g/L. He suffers from dyspnea but has no pain. He can walk only a little inside but sits or lays on the bed for the most time.