GZMB and posterior cortical atrophy: AR expression in CD8+ T cells can also influence IFN‐γ expression by regulating the transcription of IFNG and GZMB, thereby inhibiting the function of CD8+ T cells in PCa.[5] Inhibition of AR expression in CD8+ T cells may enhance the efficacy of PD‐1 targeted therapy through increased IFN‐γ expression.