FOXP3 and posterior cortical atrophy: Moreover, CHIT1, a macrophage marker, was upregulated in the combination group, which has been proposed as a potential explanation for immunotherapy resistance in PCa.[138] In women, FOXP3 can be enhanced by the AR both in vitro and in vivo, attracting Treg infiltration in vitro.[139] These findings may partially explain why ADT‐induced T cell infiltration does not improve survival outcomes in patients with PCa.[140]