Similarly, PCa cells secrete platelet‐derived growth factor‐AA, which upregulates CXCL5 expression in bone marrow‐derived mesenchymal stromal cells by suppressing the MDA9/YAP/MST axis.[81] CXCL5, in turn, facilitates PCa metastasis by promoting immunosuppressive TME. This evidence concerns the gene CXCL5 and posterior cortical atrophy.