This phenomenon included the re‐emergence of fetal‐associated endothelial cells (PLVAP/VEGFR2) and fetal‐like tumor‐associated macrophages (FOLR2).[18] Consequently, the dedifferentiation observed during tumor development and progression appears to exhibit characteristics reminiscent of a reverse organ development process.[19] These compelling studies highlight the relationship between the developmental microenvironment and TME and inspired us to investigate the immune differences between BC and PCa by comparing the developmental microenvironments and TME of the bladder and prostate. Here, KDR is linked to neoplasm.