In the context of BC, BMI1 is implicated in bladder tumorigenesis by diminishing the infiltration of CD8+ T cells.[70] BMI1 promotes chemoresistance in BC.[71] These evidence indicate that BMI1, which is regulated by AR, functions as an oncogene in both PCa and BC, contributing to chemotherapy resistance. The gene discussed is CD8A; the disease is posterior cortical atrophy.