TRIM3 and gastric cancer: ELISA and Western blot analyses supported that exosomes obtained from the serum of GC patients exhibited significantly lower TRIM3 expression compared to those from HDs (p < 0.001) (Figure3A–C).[55] These findings suggest that low TRIM3 expression in serum exosomes can serve as a biomarker for GC diagnosis, and the delivery of TRIM3 via exosomes may offer a new approach for GC therapy.