This study showed significant differences in sFlt-1 levels between CMV-transmitting and non-transmitting women; in addition, the authors reported that the sFlt1/PlGF ratio was not altered by transmission, although some cases of transmission were associated with elevated values >38, thus confirming our observation that PlGF does not undergo substantial changes in the case of placental CMV infection. Here, PGF is linked to cytomegalovirus infection.