Notably, 8 out of 11 patients (72.72%) with high ANGPTL4 levels (above the mean level of 5122.3 pg/mL) developed severe dengue or dengue hemorrhagic fever with warning signs, suggesting a potential association between plasma ANGPTL4 and dengue severity, particularly in relation to vascular leakage. The gene discussed is ANGPTL4; the disease is Dengue hemorrhagic fever.