DNAH8 and infection: Results from the Culver laboratory indicate that loss of ATPase activity (necessary for helicase activity) in a mutant 126 kDa protein causes this protein to form large granular inclusions containing tubule-like inclusions similar to those found in X-bodies behind the infection front as opposed to small inclusions formed by a native 126 kDa protein similar to VRCs observed at the infection front [71].