CREG1 and infection: In addition, among the genes that were specifically modulated after infection with vPdR-36U, 10 were upregulated (ISG15, ADAM8, TGM3, DUSP1, RCAN1, RHOB, SLC6A6, TP53INP2, CXCL-10, and CSF-1) and 3 were downregulated (CREG1, IL-6, and EDNRB) (Figure 4a and Figure 5).