CASP3 and neoplasm: The treatment with 20 mg/kg of CBD for 14 days reduced the tumor in mice with a xenograft of SK-N-SH neuroblastoma cells (an untreated group with 4.28 cm3 and CBD group 2.31 cm3, n = 12 and p < 0.05) and showed the activation of cleaved caspase-3 (p < 0.001) [7].