GSR and Hyperglycemia: Specifically, Kabach et al. used a methanolic flower extract to treat diabetic mice, finding that the treatment was able to counteract hyperglycemia-induced oxidative stress, increasing the activity of the endogenous antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and glutathione reductase (GR) in different organs [46].