A promising direction of further studies is related to the use of the combination of Rhodiola with Withania (Adaptra®), which inhibits the LTC4 signaling pathway by downregulation of expression of the leukotriene C4 synthase (LTC4S) gene and upregulating the PTGER3 gene for the treatment of allergic asthma and Alzheimer disease. Here, LTC4S is linked to early-onset autosomal dominant Alzheimer disease.