IL-1α (466 bp), IL-1β (361 bp), IL-6 (370 bp), IL-10 (387 bp), TNFα (386 bp), NCF4 (345 bp), NFKB (411 bp), TMED (408 bp), FCAMR (378 bp), iNOS (480 bp), SOD (381 bp), CAT (473 bp), GPX (416 bp), ATOX1 (430 bp) and COX18 (415 bp) PCR-DNA sequence judgments of healthy and affected rams showed variations in the amplified DNA bases linked to arthritis. The gene discussed is COX18; the disease is Arthritis.