Moreover, the HIV infection did not influence the antibody titer levels at different time points, as previously observed [21] Considering these factors, we recommend the measurement of anti-OPXV IgA antibody titers as an informative aid for the early diagnosis of MPXV infection, especially in close contacts, in order to identify individuals with an asymptomatic infection and to help prevent the spread of the disease. Here, CD79A is linked to HIV infectious disease.