TNFRSF11B and bacterial arthritis: Moreover, after depleting monocytes with etoposide, lower levels of TNF-α, IL-1β, O2−, H2O2, NO, metalloproteinase-2 (MMP-2), RANKL, and osteoprotegerin were detected, attenuating S. aureus-induced tissue destruction during septic arthritis in mice [180].